Hippocampal memory circuits in delusions

Hippocampal memory circuits have been strongly implicated in the formation and persistence of delusions in psychological disorders such as schizophrenia. According to one hypothesis, delusions may result from aberrant associative memory formation, and then may persist due to a failure to update false beliefs with new episodic information. To consider these hypotheses, we are investigating encoding and memory-based predictions in subjects with first episode psychosis both before and after they begin medication.


This project is being conducted in collaboration with Dr. Donald Goff at the NYU School of Medicine and the Shanghai Mental Health Center. 

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